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The RCBS Case Neck Brush is available in several different sizes to accommodate all of the most popular cartridge case calibers. The Small size is designed for cases between .22 and .25 caliber, while the Medium is designed for cartridge cases between .270 and .30 caliber. The Large case neck brush accommodates calibers between .35 and .45.Not only is the RCBS Case Neck Brush versatile enough to accommodate multiple caliber sizes, but it makes quick work of cleaning your cartridge cases, inside and down, removing dirt and powder residue with ease.